If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. Zetia and Crestor are both brand-name drugs. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. Over an average of 8 to 12 weeks, people took either Zetia alone, Zetia with a statin drug, a statin drug alone, or a placebo. Its not known if Zetia is safe to take during pregnancy. The generic is considered to be as safe and effective as the original drug. They can both be taken with or without food. For treatment of mixed hyperlipidemia, Zetia is indicated to reduce total cholesterol, LDL cholesterol, non-HDL cholesterol, and ApoB. Qu H, et al. Medications in the statin drug class work differently than cholesterol absorption inhibitors like Zetia. Learn about side effects, dosage, uses, interactions, and more. More research is needed to know for sure. For information on the effectiveness of Zetia, see the Zetia uses section below. People with this condition have high levels of LDL (bad) cholesterol, high levels of triglycerides, and low levels of HDL (good) cholesterol. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. 4. Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. The primary symptom of OI is lightheadedness or fainting. A malfunctioning ANS is sometimes called 'dysautonomia'. Watch Part 2 here: https://youtu.be/HPfo2QOa89YHello Friends! However, some people have reported experiencing memory loss when taking statin drugs. However, skip your missed dose if its almost time for your next dose. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Grapefruit can prevent the breakdown of these drugs in your body. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. But the condition isn't well understood, and many patients are dismissed as having anxiety, delaying diagnosis. This includes grapefruit and grapefruit juice. Total cholesterol levels were reduced by an average of: LDL (bad) cholesterol levels were reduced by an average of: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. The cause of the disorder is unknown. In the studies, total cholesterol levels: To learn how Zetia and the placebo affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Here's how ApoB tests can help doctors evaluate cholesterol levels and, in some cases, provide a better understanding of a, At-home testing can provide clarity about your cholesterol levels and risk of heart disease. The underlying cause is not known, although it sometimes follows bedrest after injury or illness. Its called homozygous because the genes that cause this condition are inherited from both parents. If you develop increased liver enzyme levels, your doctor may make changes to your treatment plan. Zetia, Baclofen, and Xanax are not known to cause itching at all, but the Xanax can cause problems with memory which you do describe. Each type is described below in more detail. * Zetia is also approved to treat these conditions in children ages 10 years and older. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. This helps prevent others, including children and pets, from taking the drug by accident. All rights reserved. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. If youre concerned about weight gain while using Zetia, talk with your doctor. Talk with your doctor about any liver problems you may have and whether its safe for you to take Zetia. Zetia contains the active drug ezetimibe. A life-changing condition called POTS, which can cause fainting, irregular heartbeats and dizziness, particularly among young women, appears to be on the rise as a result of the coronavirus pandemic. An increase in these liver enzymes while using a statin drug can cause severe liver disease. This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. You should store Zetia tablets at a room temperature of 77F (25C) in a tightly sealed container away from light. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. dark colored urine. When this happens, more cholesterol can then be cleared from your blood by your liver. Instead, it belongs to a class of drugs called cholesterol absorption inhibitors. Clinical studies involved adults and children ages 10 years and older. If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. Zetia does not cause an increase or a decrease in blood pressure. This is because fenofibrate is the only fibrate Zetia was studied with, so it isnt known whether Zetia and other fibrate drugs are safe to use together. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Zetia side effects. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. If your doctor has prescribed Zetia and youre interested in using ezetimibe instead, talk with your doctor. Read on to find out more about healthy cholesterol levels, and if a cholesterol level of 250 ml/dL is considered, Heart disease is a top cause of death in the U.S. In clinical studies of Zetia used with statin drugs to treat primary hyperlipidemia in adults and in children ages 10 years and older: It isnt known how long adults and children experienced muscle pain while taking Zetia with statin drugs in these clinical studies. It wasnt reported during studies of the drug. Most of these side effects may go away within a few days or a couple of weeks. Zetia may cause joint pain. And your doctor can use this information to adjust your treatment plan if needed. You can take Zetia at any time during the day, but try to take your dose around the same time each day. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (bad) cholesterol in certain people. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about . Temporary excursions of 59F to 86F (15C to 30C) are allowed. Zetia is approved to treat different types of high cholesterol. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Phase IV trials are used to detect adverse drug . (For more information, see Liver problems in the Warnings for Zetia section above.). So stopping Zetia may lead to an increase in your cholesterol levels. . 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. However, you may need to avoid grapefruit if you take Zetia with a statin, another type of cholesterol medication. If any of the following factors or conditions apply, you may have a higher risk of developing these muscle problems: If you have muscle-related side effects during Zetia treatment, talk with your doctor. The following information is provided for clinicians and other healthcare professionals. Zetia can be used to treat high cholesterol or homozygous sitosterolemia (a condition that causes high fat levels) in certain people. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. This can cause gallstones (hardened stones in your gallbladder). If youve had an allergic reaction to Zetia or any of its ingredients, you should not take Zetia. This is especially helpful to do when you first start taking new drugs or using a combination of treatments. So if youre taking Zetia with a statin drug, you may need to avoid eating grapefruit or drinking grapefruit juice during your treatment. If you have a history of heavy alcohol use and are taking Zetia with a statin drug, you may have a higher risk of side effects. Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. (Primary hyperlipidemia is also called primary high cholesterol.) Other side effects not listed may also occur in some patients. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. And do not stop using Zetia unless your doctor recommends it. Talk with your doctor right away if you have fever or chills with your joint pain. Talk with your doctor if you have questions about managing your blood pressure or blood sugar while using Zetia. . An increase in levels of liver enzymes doesnt usually cause any symptoms. Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. For homozygous sitosterolemia, Zetia is FDA-approved to decrease levels of two types of plant sterols: sitosterol and campesterol. For those who aren't familiar with POTS, it is an often-disabling neurological condition that causes your heart rate to rise a great deal when you are upright, and often blood pressure drops when you are upright (when it should be rising), and it causes fainting, fatigue, headache, nausea, face and hand tingling, and blood pooling in legs. Some people experience mild side effects with Zetia. (For information on side effects, see the Zetia side effects section above.). The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Symptoms of a swollen gallbladder may include: Tell your doctor if you experience gallstones while using Zetia with fenofibrate. Talk with your doctor about the risks of taking Zetia with warfarin. They can tell you about other medications that may work well for you. No, hair loss isnt a known side effect of Zetia. 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